Research Topics

1) Technological and Therapeutic Advances in Surgical Diseases

Ongoing projects:

  1. Analysis of immunoexpression of ALDH, ALCAM, CD133 and CD144 markers as probable biomarkers of stomach tumors
  2. Analysis of the recanalization index of the cerebral aneurysm submitted to endovascular treatment by embolization by saccular occlusion with coils
  3. Analysis of the tissue markers ABCB5, ALDH1, CD133 and CD44 as diagnostic factors and aggressiveness in thyroid tumors
  4. Immunohistochemical analysis of the ALDH and ALCAM marker as as biomarkers in colon tumors
  5. Immunohistochemical analysis of the AXL and ABCB5 marker as biomarkers in esophageal tumors
  6. Immunohistochemical analysis of the AXL and ABCB5 marker as biomarkers in breast tumors
  7. Immunohistochemical analysis of the AXL and ABCB5 marker as biomarkers in lung tumors
  8. Immunohistochemical analysis of the AXL and ABCB5 marker as as biomarkers in prostate tumors
  9. Immunohistochemical analysis of ABCB5 and C-MET markers as biomarkers in melanoma
  10. Immunohistochemical analysis of ALDH and ALCAM markers as biomarkers in osteosarcomas
  11. Immunohistochemical analysis of ALDH and ALCAM markers as biomarkers in tumors of the central nervous system
  12. Immunohistochemical analysis of CDX2 ALCAM markers in renal cell carcinoma
  13. Immunohistochemical analysis of C-MYC and CD133 markers as biomarkers in tumors of the central nervous system
  14. Morphometric and immunohistochemical analysis of the ALCAM ALDH marker as biomarkers in lung tumors
  15. Evaluation of leptin in the umbilical cord of newborns
  16. Correlation of the immunohistochemical expression of APC and B-Catenin with the aggressiveness in breast cancer
  17. Correlation of the immunohistochemical expression of cdx-2 and wnt3a with aggressiveness in breast cancer
  18. Correlation of immunohistochemical expression of B-Catenin, WNT3A and CDX-2 markers with aggressiveness in colon tumors
  19. Correlation of the immunohistochemical expression of the OPN and Beta-Catenin markers with the aggressiveness and tumor recurrence in meningiomas
  20. Correlation of the immunohistochemical expression of APC and Cyclin D1 with the aggressiveness of central nervous system tumors
  21. Correlation of immunohistochemical expression of B-Catenin and C-MYC with aggressiveness in tumors of the stomach
  22. Correlation of the immunohistochemical expression of C-MET t and Cyclin D1 with the aggressiveness of thyroid tumors
  23. Correlation of the immunohistochemical expression of C-MET t and Cyclin D1 with aggressiveness in breast cancer
  24. Correlation of the immunohistochemical expression of C-MET and WNT3A with aggressiveness in tumors of the central nervous system
  25. Correlation of the immunohistochemical expression of OPN and CD44 with aggressiveness in tumors of the stomach
  26. Correlation of immunohistochemical expression of WNT3A and CDX-2 with aggressiveness in thyroid tumors
  27. Involvement of catecholamines in the myocardium of rats submitted to an experimental model of portal hypertension
  28. Study of colonic diverticulosis in colonoscopies
  29. Expression of CDX-2 and B-Catenin as aggressiveness factor in tumors of the central nervous system and immunohistochemical analysis of AXL and ABCDB5 as biomarkers
  30. Expression of C-MET and Cyclin D1 and WNT3A as aggressiveness factor in tumors of stomach and immunohistochemical analysis of AXL and ABCDB5 as biomarkers in tumors of stomach
  31. Expression of C-MET as a factor of aggressiveness in colon tumors and immunohistochemical analysis of axl, C-MYC and CD133 as biomarkers
  32. Expression of C-MET and Cyclin D1 as a factor of aggressiveness in renal tumors and immunohistochemical analysis of AXL and ABCDB5 as biomarkers in renal cell carcinomas (clear cell carcinoma)
  33. Expression of C-MET and Cyclin D1 as aggressiveness factor in osteosarcomas and immunohistochemical analysis of AXL and ABCDB5 as biomarkers
  34. expression of CDX-2 and B-CATENIN as aggressiveness factor in osteosarcomas and C-MYC and CD133 as biomarkers by means of immunohistochemistry
  35. Expression of cox2, cdx-2 and muc6 as aggression factor in stomach tumor and immunohistochemical analysis of AXL and ABCB5 as biomarker
  36. Expression of OPN and APC WNT3 as an aggressive factor in osteosarcoma.

 

2) Tissue Regeneration and Immune Response in Surgical Disorders

Ongoing projects:

  1. Analysis of tissue repair when applying fibrin-rich plasma (PRF) to pedicle flaps in rabbits
  2. Analysis of the diagnostic value and accuracy of the different patterns of segmental depression in the ergometric test in the prediction of myocardial ischemia
  3. Analysis of the effects of platelet rich plasma applications in association or not with particulate autogenous bone in non-critical defects in rabbit calvaria
  4. Analysis of the effects of the PLGA / Beta-TCP carrier associated or not with TGF-Beta1 growth factor when applied to defects in rabbit calvaria
  5. Immunohistotopathological analysis of the inflammatory cellular response induced by silicone implants in the subcutaneous of rats
  6. Immunohistochemical analysis of gastric cancer and determination of micro-metastases in lymph nodes
  7. Evaluation of bone healing in rabbit calvaria using fibrin-rich plasma
  8. Evaluation of type I and II diabetes and arterial hypertension in the pre and postoperative period of bariatric surgery
  9. Evaluation of procalcitonin as an early marker of early neonatal sepsis
  10. Evaluation of the anti-inflammatory and chondroregenerating effects of intra-articular platelet rich plasma compared to non-denatured collagen, chondroitin sulfate and glucosamine sulfate in an experimental model of osteoarthritis in rats
  11. Evaluation of the levels of Pentraxin-3 in the pre and postoperative period in patients submitted to bariatric surgery.
  12. Breast carcinoma in young and super young patients: Biomarker
  13. Correlation of aneurysmal formations in the ophthalmic segment of the internal carotid artery with carotid-clinoid foramen
  14. Effect of local application of alendronate and parathyroid hormone on craniofacial bone repair - a preliminary study
  15. Effect of vitamin c supplementation on the healing time of patients submitted to neurosurgical procedures
  16. Comparative experimental study of high-weight polypropylene fabrics with micropores of low weight polypropylene with macropores and Polypropylene / Poligrecapone with macropores, used for the correction of abdominal wall of rats
  17. Histological study by biopsy of cardia, fundus and gastric antrum in the pre- and postoperative period of vertical gastrectomy in obese patients
  18. Obesity induction with sucrose in rats
  19. Nanotechnology membrane in the recovery of burns
  20. Microsurgical resection of cavernous sinus meningioma: 2-dimensional operative video
  21. Obesity in adolescence
  22. Oral and masticatory rehabilitation using osseointegrated dental implants after resistive treatment of multicystic ameloblastoma in the inferior mandible with fibular graft.
  23. Relation of the expression of p16 INK4a with recurrence of intraepithelial lesion after treatment.
  24. Bone repair in craniofacial defects treated with different doses of alendronate: histological, histomorphometric and immunohistochemical study.
  25. Retinopathy in pre and postoperative diabetic patients of bariatric surgery.

 

3) Image Innovation and Technology in Surgery

Ongoing projects:

  1. Comparative analysis between cholangiopancreator magnetic resonance and fine needle aspiration for diagnosis and follow-up of pancreatic papillary mucinous intraductal neoplasias
  2. Critical analysis of the influence of age on endoscopic therapeutic success on the bile duct
  3. Analysis of leptin in premature newborns undergoing phototherapy
  4. Evaluation by impedanciometry and manometry in the pre- and postoperative period of vertical gastrectomy
  5. Evaluation by three-dimensional tomography of the volume of the stomach on the thirtieth and ninety day postoperative day of vertical gastrectomy
  6. Comparative study of the prevalence of low and high grade intraepithelial neoplasia in colorectal superficial lesions in patients below and above 65 years
  7. Impact of the association of Propofol with Fentanyl and Midazolan on completeness of colonoscopies
  8. Investigation of the small intestine in elderly patients with bleeding of obscure origin
  9. Prevalence of Helicobacter pylori ten years ago compared to current prevalence in patients submitted to upper digestive endoscopy with urease test
  10. Prophylaxis of pancreatitis with intravenous Ketoprofen in a consecutive population of ERCP patients: A randomized double-blind, placebo-controlled study
  11. Long-term follow-up of endoscopic papilectomy in patients with tumors of the major duodenal papilla.